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Promethazine Codeine Actavis Ingredients

Promethazine Codeine Actavis Ingredients

Promethazine Codeine Actavis Ingredients, Promethazine codeine Actavis is a well-known prescription medication often used to treat symptoms such as cough, runny nose, and other upper respiratory conditions. However, it’s also one of the most misused cough syrups due to its sedative and euphoric effects. If you’re wondering what exactly goes into this powerful formula, here’s a breakdown of the promethazine codeine Actavis ingredients and how they work.

What Is Promethazine Codeine Actavis?

Promethazine with codeine syrup is a combination medication. Actavis is one of the brand names under which this drug was widely distributed before regulatory restrictions were placed on its production due to widespread abuse. It combines two key active ingredients: promethazine and codeine.


Key Ingredients in Promethazine Codeine Actavis

  1. Promethazine Hydrochloride
    • A first-generation antihistamine with strong sedative and anti-nausea properties.
    • It works by blocking histamine receptors in the brain, helping reduce allergy symptoms and motion sickness.
    • Promethazine also enhances the sedative effects of codeine.
  2. Codeine Phosphate
    • An opioid cough suppressant derived from morphine.
    • Codeine acts on the brain to reduce the urge to cough, but also has pain-relieving and sedative properties.
    • It’s a controlled substance due to its potential for addiction and misuse.
  3. Inactive Ingredients (Excipients)
    While the active ingredients do the therapeutic work, the syrup also contains several inactive ingredients that support the formulation:
    • Citric Acid – used for pH balancing and flavor enhancement.
    • Sodium Benzoate – a preservative to prevent microbial growth.
    • FD&C Red No. 40 – a coloring agent that gives the syrup its signature purple hue.
    • Artificial Flavoring – typically a berry or grape flavor to make it more palatable.
    • Sucrose and/or High Fructose Corn Syrup – sweeteners that improve taste and consistency.
    • Purified Water – the base liquid medium for the syrup.

Why the Ingredients Matter

Understanding the promethazine codeine Actavis ingredients is important for both medical and safety reasons. While effective when used as prescribed, misuse can lead to serious side effects such as drowsiness, respiratory depression, and even overdose.

Medical professionals prescribe this syrup cautiously and usually only for short-term use. Due to its popularity in recreational use (often referred to in slang as “lean” or “purple drank”), it’s also heavily regulated in many countries.


Final Thoughts

The promethazine codeine Actavis ingredients combine to create a potent medication that offers relief from certain respiratory symptoms but also carries a high risk of abuse. Whether you’re researching this drug for medical understanding or seeking to avoid potential misuse, it’s essential to be informed about what goes into it and how each ingredient affects the body.

Always consult a healthcare professional before using any medication containing codeine or promethazine, especially if you have a history of respiratory issues or substance use.


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